UNC10201652 |
| カタログ番号GC71009 |
UNC10201652 は強力なLoop 1（L 1）特異的腸管細菌β-グルクロン酸アルデヒド酵素（GUS）阻害剤であり、大腸菌GUSのIC 50値は0.117μMである。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 372495-52-8
Sample solution is provided at 25 µL, 10mM.
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UNC10201652 exhibits potently inhibitory activity against wild type E. coli with an EC50 of 74±7 nM[2].
References:
[1]. Jariwala PB, et al. Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. ACS Chem Biol. 2020 Jan 17;15(1):217-225.
[2]. Pellock SJ, et al. Gut Microbial β-Glucuronidase Inhibition via Catalytic Cycle Interception. ACS Cent Sci. 2018 Jul 25;4(7):868-879.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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