Y-27152 |
| カタログ番号GC16690 |
KATP (Kir6) チャネルオープナー Y-26763 のプロドラッグである Y-27152 は、頻脈の少ない長時間作用型の K+ チャネルオープナーであり、意識状態の高血圧ラットとイヌで降圧効果があります。
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Cas No.: 127408-30-4
Sample solution is provided at 25 µL, 10mM.
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Y-27152, a prodrug of the KATP (Kir6) channel opener Y-26763, is a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state[1][2].
References:
[1]. Nakajima T, et al. Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. J Pharmacol Exp Ther. 1992 May;261(2):730-6.
[2]. Fukunari A, et al. Y-26763 protects the canine heart from a stunning injury through opening of the KATP channels. Eur J Pharmacol. 1997 Apr 4;323(2-3):197-204.
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