Yuanhuacine |
| カタログ番号GC60389 |
Yuanhuacine (Gnidilatidin)、Daphne genkwa の花からのダフナンジテルペノイドで、広範な抗腫瘍活性があります。 Yuanhuacine は経口活性のある DNA 損傷剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 60195-70-2
Sample solution is provided at 25 µL, 10mM.
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Yuanhuacine (Gnidilatidin), a daphnane diterpenoid from the flowers of Daphne genkwa with extensive anti-tumor activity. Yuanhuacine is a DNA-damaging agent with orally active[1][2].
[1]. Ji In Kang, et al. Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells. PLoS One. 2015 Dec 11;10(12):e0144368. [2]. Ruowen Zhang, et al. The Chinese herb isolate yuanhuacine (YHL-14) induces G2/M arrest in human cancer cells by up-regulating p21 protein expression through an p53 protein-independent cascade. J Biol Chem. 2014 Mar 7;289(10):6394-403.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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