Z-VA-DL-D(OMe)-FMK (trifluoroacetate salt) (Synonyms: Caspase-1 Inhibitor V, Z-VAD-FMK, Z-VAD(OMe)-FMK, Z-Val-Ala-DL-Asp(OMe)-Fluoromethyl Ketone) |
| カタログ番号GC40125 |
Z-VA-DL-D(OMe)-FMK（Z-VAD-FMK）は、パンカスパーゼ阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Z-VA-DL-D(OMe)-FMK (Z-VAD-FMK) is a pan-caspase inhibitor. It inhibits anti-Fas antibody-induced cleavage of caspase-3 and PARP in Jurkat T lymphocytes when used at a concentration of 0.5 μM. Z-VAD-FMK (50 μM) inhibits cell death induced by TNF-α and cycloheximide co-application in HeLa cells. It also inhibits radiation-induced increases in the number of TUNEL-positive neurons in the rat hypoglossal nucleus when administered intracerebroventricularly at a dose of 2 μg per animal.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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