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JWH 146

Catalog No.GC18854

Several aminoalkylindole cannabinoids (CBs), including JWH 018 and JWH 073 , have been detected in herbal blends.

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JWH 146 Chemical Structure

Cas No.: 914458-21-2

Size Price Stock Qty
1mg
$87.00
In stock
5mg
$377.00
In stock
10mg
$610.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description of JWH 146

Several aminoalkylindole cannabinoids (CBs), including JWH 018 and JWH 073 , have been detected in herbal blends. JWH 146 is a (1-naphthoyl)pyrrole analog of JWH 018 that activates central CB1 and peripheral CB2 receptors with Ki values of 21 and 62 nM, respectively. This compound is intended for forensic and research applications.

Chemical Properties of JWH 146

Cas No. 914458-21-2 SDF
Chemical Name (1-heptyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenyl-methanone
Canonical SMILES O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCCCCCC)C(C4=CC=CC=C4)=C3
Formula C28H29NO M.Wt 395.5
Solubility DMF: 5 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of JWH 146

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.5284 mL 12.6422 mL 25.2845 mL
5 mM 0.5057 mL 2.5284 mL 5.0569 mL
10 mM 0.2528 mL 1.2642 mL 2.5284 mL
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In vivo Formulation Calculator (Clear solution) of JWH 146

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)

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