11β-HSD1-IN-11 |
| Catalog No.GC71163 |
11β-HSD1-IN-11 (화합물 c1a) 는 경쟁적인 11 베타-HSD1 억제제로서 쥐와 사람에 대한 IC50은 각각 0.34 μM과 0.13 μM이다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 859721-81-6
Sample solution is provided at 25 µL, 10mM.
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A single dose of the 11β-HSD1 inhibitor Merck 544 reduced the overall abundance of 11β-HSD1-IN-11 (Compound c1a) (15 mg/kg; oral gavage; once) in the rat liver[1].
References:
[1]. Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12(1):16268.
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