2,6-Dimethylquinoline |
| Catalog No.GC61722 |
Peucedantu praeruptorum의 뿌리에서 추출한 천연 성분인 2,6-Dimethylquinoline은 IC50이 3.3μM인 CYP1A2 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 877-43-0
Sample solution is provided at 25 µL, 10mM.
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2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 µM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 µM[1][2][3].
[1]. Laura E Korhonen, et al. Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors. J Med Chem. 2005 Jun 2;48(11):3808-15. [2]. L E Korhonen, et al. New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis. Br J Pharmacol. 2007 Apr;150(7):932-42. [3]. Cun Zhang, et al. Studies on chemical constituents from roots of Peucedanum praeruptorum II. Zhongguo Zhong Yao Za Zhi. 2006 Aug;31(16):1333-5.
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