>>Isotope-Labeled Compounds>> Deuterium>>5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6

5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6 (Synonyms: Mead Acidd6)

Catalog No.GC46680

A neuropeptide with diverse biological activities

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5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6 Chemical Structure

Cas No.: 2692624-12-5

Size 가격 재고 수량
100 μg
US$97.00
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500 μg
US$432.00
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1 mg
US$767.00
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Sample solution is provided at 25 µL, 10mM.

Description of 5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6

5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6 contains six deuterium atoms at the 5, 6, 8, 9, 11, and 12 positions. It is intended for use as an internal standard for the quantification of 5(Z),8(Z),11(Z)-eicosatrienoic acid by GC- or LC-mass spectrometry. Eicosatrienoic acid accumulates in the tissues of animals fed diets deficient in both ω-3 and ω-6 fatty acids. It can be converted to 3-series cysteinyl-leukotrienes but cannot serve as a COX substrate.1 The kidneys from essential fatty acid deficient rats are less immunogenic when transplanted, and the metabolites of eicosatrienoic acid are believed to play a role in altering the immune status of these organs.2

1.Lefkowith, J.B.Essential fatty acid deficiency: Probing the role of arachidonate in biologyAdvances in Prostaglandin, Thromboxane, and Leukotriene Research20224-231(1990) 2.Schreiner, G.F., Flye, W., Brunt, E., et al.Essential fatty acid depletion of renal allografts and prevention of rejectionScience2401032-1033(1988)

Chemical Properties of 5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6

Cas No. 2692624-12-5 SDF
Synonyms Mead Acidd6
Canonical SMILES CCCCCCCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O
Formula C20H28D6O2 M.Wt 312.5
Solubility 0.1 M Na2CO3: 1.7 mg/ml,DMF: 100 mg/ml,DMSO: 100 mg/ml,Ethanol: Miscible Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6

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1 mg 5 mg 10 mg
1 mM 3.2 mL 16 mL 32 mL
5 mM 0.64 mL 3.2 mL 6.4 mL
10 mM 0.32 mL 1.6 mL 3.2 mL
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In vivo Formulation Calculator (Clear solution) of 5(Z),8(Z),11(Z)-Eicosatrienoic Acid-d6

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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