α-CGRP (mouse, rat) (TFA) |
| Catalog No.GC72093 |
α-CGRP (mouse, rat) (TFA) 신경근육 접합에서 주로 발현되는 신경펩타이드 칼슘강하 유전자 관련 펩타이드 CGRP는 강력한 혈관 확장제이다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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α-CGRP (mouse, rat) TFA can regulate the innate lymphoid cell response in 2 groups[1].
α-CGRP (mouse, rat) TFA regulates insulin secretion and reduces the risk of type 2 diabetes[2].
α-CGRP (mouse, rat) TFA (0.25, 0.5, 1 μg/kg/min, intravenous) dose-dependent decreases mean arterial blood pressure, while heart rate and systemic vascular conduction increased, while cardiac output remained unchanged[3].
α-CGRP (mouse, rat) TFA plays an important role in the regulation of Kainic acid (KA) induced pyramid-cell death in hippocampal CA3 region[4].
References:
[1]. Whitby K, et al. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. J Virol. 2005 Jul;79(14):8698-706.
[2]. Xu H, et al. Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. Immunity. 2019 Oct 15;51(4):696-708.e9.
[3]. Arulmani U, et al. Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats. Basic Clin Pharmacol Toxicol. 2004 Jun;94(6):291-7.
[4]. Park SH, et al. Role of α-CGRP in the regulation of neurotoxic responses induced by kainic acid in mice. Peptides. 2013 Jun;44:158-62.
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