AC-099 hydrochloride |
| Catalog No.GC71300 |
AC-099 hydrochloride (화합물 3)은 선택적 NPFF2R 완전 agonist (EC50=1189 nM)와 NPFF1R 부분 agonist (EC50=2370 nM)이다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 849335-07-5
Sample solution is provided at 25 µL, 10mM.
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AC-099 hydrochloride (compound 3; 30 mg/kg; i.p.; single) completely attenuates spinal nerve ligation (SNL)-induced hypersensitivity in rats[2].
References:
[1]. Findeisen M, et al. Selective mode of action of guanidine-containing non-peptides at human NPFF receptors. J Med Chem. 2012 Jul 12;55(13):6124-36.
[2]. Gaubert G, et al. Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists. J Med Chem. 2009 Nov 12;52(21):6511-4.
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