>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>Adipic acid-d4

Adipic acid-d4

Catalog No.GC72586

Adipic acid-d4는 Adipic acid로 표기된 중수소이다.

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Adipic acid-d4 Chemical Structure

Cas No.: 121311-78-2

Size 가격 재고 수량
5 mg
US$36.00
재고 있음
10 mg
US$59.00
재고 있음
25 mg
US$113.00
재고 있음
50 mg
US$180.00
재고 있음
100 mg
US$288.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Adipic acid-d4 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. G.Frauendienst-Egger, Friedrich K. Trefz (2017). MetaGene: Metabolic & Genetic Information Center. METAGENE consortium.

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