Amino-PEG9-alcohol |
| Catalog No.GC67141 |
아미노-PEG9-알코올은 PROTAC 합성에 사용할 수 있는 PEG 기반 PROTAC 링커입니다.821d96072c2d58d8970e76f526b0f6b8
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Cas No.: 15332-95-3
Sample solution is provided at 25 µL, 10mM.
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Amino-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Sitterley KA, et al. Identification of Proprietary Amino Ethoxylates in Hydraulic Fracturing Wastewater Using Liquid Chromatography/Time-of-Flight Mass Spectrometry with Solid-Phase Extraction. Anal Chem. 2018 Sep 18;90(18):10927-10934.
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