Angiotensin I (human, rat, mouse) (trifluoroacetate salt) |
Catalog No.GC42808 |
Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II by angiotensin-converting enzyme (ACE).
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Sample solution is provided at 25 µL, 10mM.
Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II by angiotensin-converting enzyme (ACE). It binds to angiotensin receptors in human myometrium membrane preparations (Kd = 11.2 nM) and increases renal vascular resistance in isolated rat kidney (EC50 = 10.5 nM). In vivo, angiotensin I (5 μg/kg, i.c.v.) increases mean arterial pressure (MAP) and plasma arginine vasopressin (AVP) level in fetal ewes.
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