Antibacterial agent 131 |
| Catalog No.GC71202 |
Antibacterial agent 131는 퀴놀린 유도체이다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Antibacterial agent 131 (compound 4m) has antimicrobial activity with MIC90 values of 9.81 μg/mL for Escherichia coli ATCC 35218, E. coli ATCC 25922, Staphylococcus aureus ATCC 6538, and methicillin-resistant S. aureus (MRSA), respectively[1].
Antibacterial agent 131 has anti-candida effect with MIC90 values of ≤0.06, 0.24, 1.95, and 1.95 μg/mL for Candida krusei ATCC 6258, Candida parapsilosis ATCC 22019, Candida albicans ATCC 24433, and C. glabrata ATCC 90030, respectively[1].
Antibacterial agent 131 (24 h) has low cytotoxicity with an IC50 value of 34.51 μM in NIH/3T3 cells[1].
Antibacterial agent 131 (0.06-3.91 μg/mL) inhibits DNA-Gyrase Enzyme against E. coli[1].
Antibacterial agent 131 has antifungal activity via blocking ergosterol production[1].
References:
[1]. Asaf Evrim Evren, et al. Investigation of Novel Quinoline-Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches. ACS Omega. 2022 Dec 29;8(1):1410-1429.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *