Antroquinonol |
| Catalog No.GC71544 |
Antroquinonol ((+) - Antroquinonol 버섯 Antrodia camphorata에서 추출 한 범퀴논 유도체로서 간을 보호하고 항염 및 항암 작용을 합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1010081-09-0
Sample solution is provided at 25 µL, 10mM.
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Antroquinonol is a ubiquinone derivative from A.camphorata[2].
Antroquinonol inhibits cell growth and suppresses the migratory/invasive ability of human colon cancer cells. Antroquinonol at high concentrations (40-80 μM) exhibits growth inhibitory activities in the three colon cancer cell lines, whereas low concentrations of Antroquinonol (2.5-20 μM) shows modest growth inhibition[2].
Antroquinonol possesses the ability to inhibit breast cancer migration/invasion by inhibiting the EMT and MMP-9 gene expression[2].
Antroquinonol has inducible nitric oxide synthase (iNOS) inhibitory activity in lipopolysaccharide (LPS)-activated macrophages, anti-inflammatory activity in macrophage cell cultures by reducing the production of tumor necrosis factor-α and interleukin (IL)-1β, and anti-cancer activity against hepatoma cells[3].
Antroquinonol is a major active component of a mushroom, namely Antrodia camphorate, and it has inhibitory effects on nitric oxide production and inflammatory reactions.Antroq ameliorates proteinuria, improves renal function, and decreases renal lesions, including EPHL, a severe index of glomerular injury, in FSGS mice[3].
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