BBT |
Catalog No.GC72475 |
BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 445000-45-3
Sample solution is provided at 25 µL, 10mM.
BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ)-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathway.
References:
[1]. Yao XG, et al. BBT improves glucose homeostasis by ameliorating 尾-cell dysfunction in type 2 diabetic mice. J Endocrinol. 2015 Mar;224(3):327-41.
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