>>Signaling Pathways>> PROTAC>> Ligand for Target Protein for PROTAC>>BI-4464

BI-4464

Catalog No.GC34488

BI-4464는 IC50이 17nM인 PTK2/FAK의 고도로 선택적인 ATP 경쟁 억제제입니다. PROTAC용 PTK2 리간드.

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BI-4464 Chemical Structure

Cas No.: 1227948-02-8

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$407.00
재고 있음
5mg
US$333.00
재고 있음
10mg
US$536.00
재고 있음
50mg
US$1,665.00
재고 있음
100mg
US$2,479.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1]. IC50: 17 nM (PTK2/FAK)[1].

[1]. Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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