Biotin-PEG3-acid |
| Catalog No.GC62231 |
Biotin-PEG3-acid는 PROTAC 합성에 사용할 수 있는 비오틴 표지 PEG 기반 PROTAC 링커입니다.
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Cas No.: 252881-76-8
Sample solution is provided at 25 µL, 10mM.
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Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
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