Biotinylated-JQ1 (Synonyms: Biotin-JQ1) |
| Catalog No.GC64789 |
Biotinylated-JQ1(Biotin-JQ1)은 BRD4의 브로모도메인에 대해 높은 친화성을 가진 JQ1의 바이오틴화된 유도체입니다. Biotinylated-JQ1은 0.4μM의 EC50으로 MM1.S 다발성 골수종 세포 증식을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1635437-52-3
Sample solution is provided at 25 µL, 10mM.
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Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1].
Biotinylated-JQ1 (0.1 nM-100 μM; 72 hours) inhibits MM1.S cell proliferation with an EC50 of 0.4 μM[1].
[1]. Lars Anders, et al. Genome-wide localization of small molecules. Nat Biotechnol. 2014 Jan;32(1):92-6.
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