BL-918 |
| Catalog No.GC39481 |
BL-918은 EC50이 24.14nM인 경구 활성 UNC-51-유사 키나제 1(ULK1) 활성제입니다.
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Cas No.: 2101517-69-3
Sample solution is provided at 25 µL, 10mM.
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BL-918 (compound 33i) is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 exerts its cytoprotective autophagic effect by targeting ULK complex. BL-918 has the potential for Parkinson's disease (PD) treatment[1].
[1]. Ouyang L, et al. Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment. J Med Chem. 2018 Apr 12;61(7):2776-2792.
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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