BMAP 28 (bovine) (trifluoroacetate salt) |
Catalog No.GC90557 |
항균 펩타이드
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Bovine myeloid antimicrobial peptide (BMAP) 28 is a synthetic antimicrobial peptide that corresponds to amino acids 132-158 of bovine cathelicidin-5.1 It is active against the bacteria E. coli, S. aureus, methicillin-resistant S. aureus (MRSA), and S. epidermidis and the fungus C. albicans (MICs = 2, 2, 4, 1, and 8 µM, respectively). BMAP 28 induces inner membrane permeabilization in E. coli when used at a concentration of 200 nM. It reduces viral replication of herpes simplex virus 1 (HSV-1) in Vero 76-infected cells when used at a concentration of 5 µM.2 It induces hemolysis of isolated human erythrocytes and is cytotoxic to isolated human neutrophils when used at a concentration of 30 µM.1 BMAP 28 (0.8 mg/kg) increases survival in E. coli- or MRSA-infected mice but not P. aeruginosa-infected mice.2
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