Boc-NH-PEG2-CH2COOH |
| Catalog No.GC60653 |
HBC514는 비형광 HBC 유사체이지만 Pepper RNA 앱타머와 단단한 복합체를 형성할 때 강한 녹색 형광을 방출합니다. HBC514-Pepper 복합체는 RNA의 시각화를 가능하게 하며 형광은 살아있는 Pepper 태그가 지정된 세포에서 간단한 세척 및 염색으로 유연하게 변경될 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 108466-89-3
Sample solution is provided at 25 µL, 10mM.
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Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020 Feb 1;187:111952.
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