ML-9 |
Catalog No.GC49440 |
ML-9는 Akt 키나제의 선택적이고 강력한 억제제로 미오신 경쇄 키나제(MLCK) 및 기질 상호작용 분자 1(STIM1) 활성을 억제합니다. ML-9 억제는 각각 4, 32 및 54μM의 Ki 값으로 MLCK, PKA 및 PKC 활성을 억제합니다. ML-9는 autophagosome 형성을 자극하고 분해를 억제하여 autophagy를 유도합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 105637-50-1
Sample solution is provided at 25 µL, 10mM.
ML-
1.Ito, S., Kume, H., Honjo, H., et al.ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealisEuropean Journal of Pharmacology486325-333(2004) 2.Smith, U., Carvalho, E., Mosialou, E., et al.PKB inhibition prevents the stimulatory effect of insulin on glucose transport and protein translocation but not the antilipolytic effect in rat adipocytesBiochemical and Biophysical Research Communications268315-320(2000)
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