>>Signaling Pathways>> GPCR/G protein>> mGluR >>CBiPES

CBiPES

Catalog No.GC70277

CBiPES은 92.8 nM의 EC50 값을 갖는 강력한 mGlu2 양성 알로스테릭 변조제이다.

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CBiPES Chemical Structure

Cas No.: 353235-01-5

Size 가격 재고 수량
5 mg
US$180.00
재고 있음
10 mg
US$297.00
재고 있음
25 mg
US$585.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
CBiPES is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases.

References:
[1]. Johnson MP, et al. Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s). Psychopharmacology (Berl). 2005 Apr;179(1):271-83.
[2]. Frouni I, et al. Effect of the mGlu2 positive allosteric modulator CBiPES on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset. J Neural Transm (Vienna). 2021 Jan;128(1):73-81.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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