>>Signaling Pathways>> PROTAC>> Ligand for E3 Ligase>>CC-99282

CC-99282 (Synonyms: CC-99282)

Catalog No.GC64851

CC-99282는 강력한 경구 활성 소뇌(CRBN) E3 리가제 조절제(CELMoD)입니다. CC-99282는 CRBN을 선택하여 Ikaros와 Aiolos의 강력하고 표적화된 분해를 유도합니다. CC-99282는 비호지킨 림프종 연구에 사용할 수 있습니다.

Products are for research use only. Not for human use. We do not sell to patients.

CC-99282 Chemical Structure

Cas No.: 2379572-34-4

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$530.00
재고 있음
1mg
US$180.00
재고 있음
5mg
US$450.00
재고 있음
10mg
US$720.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CC-99282 is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). CC-99282 co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. CC-99282 can be used for researching non-Hodgkin lymphomas[1].

[1]. J.-M. Michot, et al. A PHASE 1, MULTICENTER, OPEN-LABEL STUDY OF CC-99282 ALONE AND IN COMBINATION WITH RITUXIMAB IN PATIENTS WITH RELAPSED OR REFRACTORY NON-HODGKIN LYMPHOMAS. Hematological Oncology. Volume 39, Issue S2, Jun. 2021.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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