Ceefourin 1 |
| Catalog No.GC50287 |
Ceefourin 1은 강력하고 고도로 선택적인 MRP4(다제 내성 단백질 4) 억제제입니다. Ceefourin 1은 광범위한 MRP4 기질의 수송을 억제하지만 다른 ABC 수송체에 비해 MRP4에 대해 매우 선택적입니다. Ceefourin 1은 benzothiazol이며 주로 고위험 신경모세포종에 대한 화학감작제로 사용됩니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 315702-40-0
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC50 = 2.6 μM). Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 .
Cheung et al (2014) High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem.Pharmacol. 91 97 PMID:24973542
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *