ChemR23-IN-1 |
Catalog No.GC70594 |
ChemR23-IN-1 (화합물 2)는 사람과 생쥐 ChemR23의 IC50이 각각 38nM과 100nM의 ChemR23 억제제이다.
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Cas No.: 2378640-10-7
Sample solution is provided at 25 µL, 10mM.
ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro.
References:
[1]. Takamichi Imaizumi, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622.
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