Chloroguanabenz (acetate) |
Catalog No.GC43245 |
Chloroguanabenz is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz.
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Sample solution is provided at 25 µL, 10mM.
Chloroguanabenz is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz . It inhibits prion formation in yeast and mammalian cell-based assays. Chloroguanabenz reduces the levels of both soluble and aggregated forms of the truncated Huntingtin derivative Htt48 in an HEK293T cellular model of Huntington's disease.
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