CID44216842 (Synonyms: Cdc42-IN-1) |
| Catalog No.GC39810 |
CID44216842(Cdc42-IN-1)는 강력한 Cdc42 선택적 구아닌 뉴클레오티드 결합 납 억제제입니다. Cdc42 WT 및 Cdc42Q61L 돌연변이에 대한 EC50은 GTP 결합 분석에서 각각 1.0 및 1.2 μM입니다. Cdc42 WT 및 Cdc42Q61L 돌연변이에 대한 EC50은 GDP 결합 분석에서 각각 0.3 및 0.5 μM입니다. 분자 프로브로 사용하십시오.
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Cas No.: 1222513-26-9
Sample solution is provided at 25 µL, 10mM.
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CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe[1].
[1]. Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43.
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