CL2A |
| Catalog No.GC62899 |
CL2A는 절단 가능한 복잡한 PEG8 및 트리아졸 함유 PABC-펩티드-mc 링커입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2616704-22-2
Sample solution is provided at 25 µL, 10mM.
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CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].
[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC). Teknisk- naturvetenskaplig fakultet
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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