CPPA-TPP (Synonyms: CPPA-Triphenylphosphonium,4-Cyano-4-(phenylcarbonothioylthio)pentanoic Acid-TPP,4-Cyano-4-(phenylcarbonothioylthio)pentanoic-Triphenylphosphonium) |
| Catalog No.GC91800 |
CPPA-TPP is a chain transfer agent conjugated to the mitochondria-targeting moiety triphenylphosphonium (TPP).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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CPPA-TPP is a chain transfer agent conjugated to the mitochondria-targeting moiety triphenylphosphonium (TPP).1 It has been used in the synthesis of reactive oxygen species-sensitive mitochondrial targeting polyprodrugs containing the topoisomerase I inhibitor camptothecin.
References:
[1].Zhang, W., Hu, X., Shen, Q., et al.Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapyNat. Commun.10(1)1704(2019).
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