Crocin IV |
Catalog No.GC62912 |
크로신 IV (디크로신)은 크로세틴 글리코사이드로, 카로테노이드 색소입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 57710-64-2
Sample solution is provided at 25 µL, 10mM.
Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity[1].
Crocin IV (Dicrocin; 10 μM; 24 hours) has little or no effect on the prolongation of cell survival in PC12 cell[1]. Crocin IV enhances γ-GCS mRNA expression in serum-deprived and hypoxic PC12 cells[1]. Measurements of cell viability, peroxidized membrane lipids and caspase-3 activity showed that the rank order of the neuroprotective potency at a concentration of 10 μM is crocin>tricrocin>dicrocin and picrocrocin (the latter two crocins had a little or no potency)[1].
[1]. Takashi Ochiai, et al. Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo. Biochim Biophys Acta. 2007 Apr;1770(4):578-84.
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