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CU06-1004

Catalog No.GC71363

CU06-1004 (Sac-1004)는 경구용 활성 내피 기능 장애 차단제입니다.

Products are for research use only. Not for human use. We do not sell to patients.

CU06-1004 Chemical Structure

Cas No.: 1296734-08-1

Size 가격 재고 수량
1 mg
US$360.00
재고 있음
5 mg
US$891.00
재고 있음

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Based on customer reviews.

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
CU06-1004 (Sac-1004) is an orally active endothelial dysfunction blocker. CU06-1004 ameliorates endothelial dysfunction by inhibiting hyperpermeability and inflammation, and is potent in inhibiting vascular leakage and inflammation in various animal models, such as diabetic retinopathy, stroke, cancer, and inflammatory bowel disease. CU06-1004 ameliorates CDAA-induced mouse model of NASH. CU06-1004 also improves cardiac function.

References:
[1]. Zhang H, et al. CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia-reperfusion injury. Exp Mol Med. 2022 Jan;54(1):23-34.
[2]. Kim Y, et al. Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury. J Inflamm (Lond). 2023 Apr 6;20(1):13.
[3]. Bae CR, et al. Correction: The endothelial dysfunction blocker CU06-1004 ameliorates choline-deficient L-amino acid diet-induced non-alcoholic steatohepatitis in mice. PLoS One. 2021 Apr 5;16(4):e0249747.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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