>>Signaling Pathways>> TGF-β / Smad Signaling>> TGF-β Receptor>>Dalutrafusp alfa

Dalutrafusp alfa

Catalog No.GC72448

Dalutrafusp alfa (AGEN-1423; GS-1423) is a specific bifunctional antibody against CD73 and TGF-β, which is involved in the immunosuppressive pathway.

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Dalutrafusp alfa Chemical Structure

Cas No.: 2419918-89-9

Size 가격 재고 수량
1 mg
US$378.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Dalutrafusp alfa (AGEN-1423; GS-1423) is a specific bifunctional antibody against CD73 and TGF-β, which is involved in the immunosuppressive pathway.

References:
[1]. Anthony W Tolcher, et al. Phase 1 first-in-human study of dalutrafusp alfa, an anti-CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors. J Immunother Cancer. 2023 Feb;11(2):e005267.

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