Dapaconazole |
| Catalog No.GC62304 |
항진균제인 Dapaconazole은 1.4μM의 IC50으로 sterol 14α-demethylase cytochrome P450 활성을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1269726-67-1
Sample solution is provided at 25 µL, 10mM.
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Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1].
Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 ± 0.3 μM[1].
Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 %[1].
[1]. Juliana SP, et al. Pharmacokinetics of Dapaconazole, A Novel Antifungal Agent, in Beagle Dogs and Inhibition of Cytochrome P450 Family 51. J Eur Acad Dermatol Venereol. 2018 Jun 10.
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