>>Signaling Pathways>> PROTAC>>DBCO-PEG4-amine

DBCO-PEG4-amine

Catalog No.GC39605

DBCO-PEG4-아민은 PEG 기반 PROTAC 링커로 PROTAC 합성에 사용할 수 있습니다. DBCO-PEG4-아민은 항체-약물 접합체(ADC) 합성에 사용되는 절단 가능한 ADC 링커입니다. DBCO-PEG4-아민은 FPM-PEG4-DBCO(동종이작용성 아지드-아지드 가교제)의 합성에 사용될 수 있습니다.

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DBCO-PEG4-amine Chemical Structure

Cas No.: 1840886-10-3

Size 가격 재고 수량
50mg
US$441.00
재고 있음
100mg
US$702.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].

[1]. Florinas S, et al. A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments. Biomacromolecules. 2016 May 9;17(5):1818-33.

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