Deltamethrin-d5 (Synonyms: Decamethrin-d5) |
Catalog No.GC63475 |
Deltamethrin-d5(Decamethrin-d5)는 Deltamethrin으로 표시된 중수소입니다. 신경독성 피레스로이드계 살충제인 Deltamethrin(Decamethrin)은 뒷다리 경직 및 무도변위를 포함하는 가역적인 일련의 운동 증상을 랫트에서 생성합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2140301-99-9
Sample solution is provided at 25 µL, 10mM.
Deltamethrin-d5 (Decamethrin-d5) is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis[1][2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kavlock R, et al. Toxicity studies with decamethrin, a synthetic pyrethroid insecticide. J Environ Pathol Toxicol. 1979;2(3):751-765.;Ray DE. An EEG investigation of decamethrin-induced choreoathetosis in the rat. Exp Brain Res. 1980;38(2):221-227.
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