Dopamine 3-O-Sulfate (Synonyms: DA-3S, Dopamine 3-Sulfate) |
Catalog No.GC49166 |
A metabolite of dopamine
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Cas No.: 51317-41-0
Sample solution is provided at 25 µL, 10mM.
Dopamine 3-O-sulfate is a metabolite of the endogenous catecholamine dopamine .1 It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3.2 Dopamine 3-O-sulfate is found at higher levels in the brain and circulation than dopamine 4-O-sulfate.1,2
1.Suominen, T., Uutela, P., Ketola, R.A., et al.Determination of serotonin and dopamine metabolites in human brain microdialysis and cerebrospinal fluid samples by UPLC-MS/MS: Discovery of intact glucuronide and sulfate conjugatesPLoS One8(6)e68007(2013) 2.ItÄaho, K., Alakurtti, S., Yli-Kauhaluoma, J., et al.Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulationBiochem. Pharmacol.74(3)504-510(2007)
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