DOTATATE acetate |
| Catalog No.GC61528 |
DOTATATE 아세테이트는 DOTA 결합 펩타이드입니다. DOTATATE 아세테이트는 양전자 방출 단층 촬영(PET) 영상 및 펩티드 수용체 방사성 핵종 요법(PRRT)을 위한 방사성 핵종으로 라벨링될 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 177943-89-4
Sample solution is provided at 25 µL, 10mM.
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DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide therapy (PRRT)[1][2][3][4].
177Lu-DOTATATE shows excellent antitumor effects in rats[1].
[1]. Jong M, et, al. Combination radionuclide therapy using 177Lu- and 90Y-labeled somatostatin analogs. J Nucl Med. 2005 Jan;46 Suppl 1:13S-7S. [2]. Gains JE, et, al. 68Ga-DOTATATE and 123I-mIBG as imaging biomarkers of disease localisation in metastatic neuroblastoma: implications for molecular radiotherapy. Nucl Med Commun. 2020 Aug 10. [3]. Breeman WAP, et, al. Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities. Eur J Nucl Med Mol Imaging. 2003 Jun;30(6):917-20. [4]. Reubi JC, et, al. Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use. Eur J Nucl Med. 2000 Mar;27(3):273-82.
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