Dox-btn2 |
| Catalog No.GC71260 |
Dox-btn2 는 아마이신의 바이오매스 유도체로 3'-NH 2곳에서 아마이신과 결합할 때 바이오매스 표시를 하고 있다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3026061-31-1
Sample solution is provided at 25 µL, 10mM.
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Dox-btn2 is a biotinylated derivative of Doxorubicin , with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm.
Dox-btn2 (1 μM; 6 h; Exc=531/40 nm and Emi=593/40 nm) exhibits visualization in U2OS cells, helps in situ mapping with Chem-map of small-molecule interactions with DNA and chromatin proteins[1].
References:
[1]. Yu Z, et al. Chem-map profiles drug binding to chromatin in cells. Nat Biotechnol. 2023 Jan 23.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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