DSM265 |
Catalog No.GC32097 |
DSM265는 P.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1282041-94-4
Sample solution is provided at 25 µL, 10mM.
DSM265 is a PfDHODH inhibitor with an IC50 of 8.9 nM. DSM265 can also inhibit the growth of P. falciparum 3D7 parasites with an EC50 of 4.3 nM.
[1]. Kokkonda S, et al. Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparumDihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity. J Med Chem. 2016 Jun 9;59(11):5416-31.
Average Rating: 5
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