E3 ligase Ligand-Linker Conjugates 4 (Synonyms: VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4) |
Catalog No.GC30071 |
E3 리가제 리간드-링커 접합체 4는 PROTAC 기술에 사용되는 (S,R,S)-AHPC 기반 VHL 리간드 및 4-단위 PEG 링커를 통합하는 합성된 E3 리가제 리간드-링커 접합체입니다.
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Cas No.: 1797406-81-5
Sample solution is provided at 25 µL, 10mM.
E3 ligase Ligand-Linker Conjugates 4 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.
E3 ligase Ligand-Linker Conjugates 4 together with JQ1 triggers the intracellular destruction of BET proteins[1].
[1]. Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chemical Biology (2015), 10(8), 1770-1777.
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