Eact |
Catalog No.GC18142 |
Eact는 TMEM16A의 선택적이고 강력한 활성제이며 감각 통각 수용체에서 TRPV1 채널을 직접 활성화하고 가려움증, 급성 통각 및 열 과민증을 유발합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 461000-66-8
Sample solution is provided at 25 µL, 10mM.
TMEM16A (ANO1) calcium-activated chloride channel (CaCC) activator (EC50 = 3 μM). Also transient receptor potential vanilloid 1 (TRPV1) channel activator (EC50 = 11.6 μM). Ca2+-independent. Displays no effect on CFTR Cl- or ENaC Na+ conductance. Stimulates submucosal gland secretion in human bronchi.
Average Rating: 5
(Based on Reviews and 28 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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