Echitamine chloride |
| Catalog No.GC63871 |
Echitamine chloride는 강력한 항종양 활성을 가진 Alstonia에 존재하는 주요 모노테르펜 인돌 알칼로이드입니다. Echitamine chloride는 DNA 단편화와 세포 사멸을 유도합니다. Echitamine chloride는 IC50이 10.92 μ인 췌장 리파제를 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6878-36-0
Sample solution is provided at 25 µL, 10mM.
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Echitamine chloride is the major monoterpene indole alkaloid present in Alstonia with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC50 of 10.92 µM[1][2].
[1]. Ganesh Chandra Jagetia, et al. Evaluation of the Cytotoxic Effect of the Monoterpene Indole Alkaloid Echitamine In-Vitro and in Tumour-Bearing Mice. J Pharm Pharmacol. 2005 Sep;57(9):1213-9.
[2]. Ginson George, et al. Development and Validation of a New HPTLC-HRMS Method for the Quantification of a Potent Pancreatic Lipase Inhibitory Lead Echitamine From Alstonia scholaris. Nat Prod Res. 2019 Dec 24;1-5.
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