Elacestrant (S enantiomer) (Synonyms: RAD1901 S enantiomer) |
| Catalog No.GC62379 |
Elacestrant S 거울상 이성질체(RAD1901 S 거울상 이성질체)는 Elacestrant의 저활성 거울상 이성질체입니다. Elacestrant(RAD1901)는 ERα에 대해 IC50 값이 48 및 870nM인 선택적 경구용 에스트로겐 수용체(ERR) 분해제입니다. 및 ERβ, 각각.
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Cas No.: 2309762-29-4
Sample solution is provided at 25 µL, 10mM.
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Elacestrant S enantiomer (RAD1901 S enantiomer) is an low activity enantiomer of elacestrant. Elacestrant (RAD1901) is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively[1].
[1]. Garner F, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56.
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