>>Signaling Pathways>> Proteases>> Drug Metabolite>>ent-Ezetimibe

ent-Ezetimibe

Catalog No.GC70728

ent-Ezetimibe (ent SCH 58235) 는 이접맥포의 RRS 대영 이구체이다.

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ent-Ezetimibe Chemical Structure

Cas No.: 1376614-99-1

Size 가격 재고 수량
5 mg
US$504.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potentNrf2 activator.

References:
[1]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.
[2]. Yijun Zhu, et al. Efficient and scalable process for the synthesis of antihypercholesterolemic drug ezetimibe. An International Journal for Rapid Communication of Synthetic Organic Chemistry

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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