ErSO-DFP |
| Catalog No.GC65425 |
ErSO-DFP는 예상 전개 단백질 반응(a-UPR) 활성제입니다. ErSO-DFP는 ErSO보다 더 넓은 선택 창으로 에스트로겐 수용체 알파 양성(ERα+) 암 세포에 대한 선택성을 향상시켰습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2768139-76-8
Sample solution is provided at 25 µL, 10mM.
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ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator. ErSO-DFP has enhanced selectivity for estrogen receptor alpha-positive (ERα+) cancer cells with a wider selectivity window than ErSO.ErSO-DFP displays antitumor activity and leads to profound regression of MCF-7 tumors in mice model[1].
[1]. Matthew W Boudreau, et al. Activators of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer. J Med Chem. 2022 Mar 10;65(5):3894-3912.
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