Fasentin |
Catalog No.GC43654 |
강력한 포도당 흡수 억제제인 Fasentin은 GLUT-1/GLUT-4 수송체를 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 392721-37-8
Sample solution is provided at 25 µL, 10mM.
Fasentin is an inhibitor of glucose transport. It partially inhibits glucose uptake in U937 and DU145 cells when used at concentrations ranging from 15 to 80 µM. Fasentin sensitizes PPC-1 prostate cancer and U937 leukemia cells, but not DU145 prostate cancer cells, to cell death induced by the Fas receptor activator CH-11 activating anti-Fas antibody (FAS). It also increases the expression of AspSyn and PCK2, genes associated with glucose deprivation, in PPC-1 cells and halts the cell cycle at the G0/G1 phase in U937 cells when used at concentrations of 50 and 40 µM, respectively.
Average Rating: 5
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