Fenipentol |
| Catalog No.GC60835 |
조미료 및 염료로 사용되는 Curcuma longa 성분의 합성 유도체인 Fenipentol(1-Phenyl-1-pentanol).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 583-03-9
Sample solution is provided at 25 µL, 10mM.
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Fenipentol (1-Phenyl-1-pentanol), a synthetic derivative of an ingredient of Curcuma longa that is used as a condiment and dye. Fenipentol is also an orally active choleretic agent that plays an important role in release of secretin, gastrin, and pancreatic secretion of bicarbonate and protein[1][2][3].
Fenipentol (PHP) (50-200 mg/kg; p.o. and intraduodenal administration) increases the secretory volume of pancreatic juice and the output of protein in rats[2].Fenipentol (50-200 mg/kg for i.p. and 5-10 mg/kg for i.v.) considerably increases biliary secretion in rats[2].Fenipentol (25-200 mg/kg; intraduodenal administration) stimulates the pancreatic secretion in the canine[2].
[1]. Fregnan GB, et, al. Therapeutic properties of dihydroxy-dibutylether on sub-acute liver damage induced by several hepatotoxic agents in rats. Int J Tissue React. 1982; 4(4): 309-18. [2]. Wakabayashi T, et, al. [Effect of 1-phenyl-1-hydroxy-n-pentane on pancreatic secretion in the rat and the dog]. Nihon Yakurigaku Zasshi. 1971 Nov; 67(6): 637-47. [3]. Sharma A, et, al. Biocatalytic and electrochemical reduction of selected phenyl alkanones with antibacterial activity of the corresponding phenyl alkanols. Ijabpt Com, 2011.
| Cas No. | 583-03-9 | SDF | |
| Canonical SMILES | OC(CCCC)C1=CC=CC=C1 | ||
| Formula | C11H16O | M.Wt | 164.24 |
| Solubility | Chloroform: 125 mg/mL (761.08 mM); DMSO: 100 mg/mL (608.87 mM) | Storage | 4°C, away from moisture and light |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 6.0887 mL | 30.4433 mL | 60.8865 mL |
| 5 mM | 1.2177 mL | 6.0887 mL | 12.1773 mL |
| 10 mM | 0.6089 mL | 3.0443 mL | 6.0887 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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