Fuzapladib |
Catalog No.GC71535 |
Fuzapladib (IS-741)는 경구용 활성 백혈구 기능 관련 항원 1형(LFA-1) 활성화 억제제로, 백혈구 접착 분자의 일종이다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 141283-87-6
Sample solution is provided at 25 µL, 10mM.
Fuzapladib (IS-741) (1 μM, 3 h) can significantly inhibit the adhesion of HL-60 cells to HUVEC under the stimulation of lipopolysaccharide[3].
Fuzapladib (IS-741) (p.o., 50 mg/kg, 7 days) inhibits neutrophil infiltration into inflamed lesions, and is effective for attenuating rat trinitrobenzene sulfonic acid (TNBS) ileitis[4].
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