>>Signaling Pathways>> Metabolism>> Phospholipase>>Fuzapladib

Fuzapladib

Catalog No.GC71535

Fuzapladib (IS-741)는 경구용 활성 백혈구 기능 관련 항원 1형(LFA-1) 활성화 억제제로, 백혈구 접착 분자의 일종이다.

Products are for research use only. Not for human use. We do not sell to patients.

Fuzapladib Chemical Structure

Cas No.: 141283-87-6

Size 가격 재고 수량
1 mg
US$90.00
재고 있음
5 mg
US$198.00
재고 있음
10 mg
US$297.00
재고 있음
25 mg
US$558.00
재고 있음
50 mg
US$747.00
재고 있음

Tel:(909) 407-4943 Email: sales@glpbio.com

고객 리뷰

Based on customer reviews.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site.

Fuzapladib (IS-741) (1 μM, 3 h) can significantly inhibit the adhesion of HL-60 cells to HUVEC under the stimulation of lipopolysaccharide[3].

Fuzapladib (IS-741) (p.o., 50 mg/kg, 7 days) inhibits neutrophil infiltration into inflamed lesions, and is effective for attenuating rat trinitrobenzene sulfonic acid (TNBS) ileitis[4].

리뷰

Review for Fuzapladib

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for Fuzapladib

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.